Our history is closely associated with the Greenville Women's College as well. The area just behind the Coca-Cola Plant was a working dairy into the 20th century. The dairy supplied products to the college and offered stabling for the horses belonging to the employees of the college. In addition to the dairy, there were working vineyards located in and around the neighborhood into the early 20th century. Of course, the proximity of the neighborhood to the college made it an attractive place to live for employees of the college.

The Heritage Neighborhood has a rich cultural history. For most of its 120-year history it served as the center of the Greek culture in Greenville. Many of the residents attended St. George Greek Orthodox Church and chose to live nearby, in the Heritage Neighborhood. Today the Greek community is well represented in the neighborhood. In fact, several neighbors from the Greek community have been life-long residents. Some of Greenville's most prominent Greek residents grew up in the neighborhood. Nick Theodore, prominent in South Carolina government and a past Lt. Governor grew up on Barrett St. The Francis family, Greenville entrepreneurs and philanthropists were long-time residents of Atwood Street. Sadly their boyhood home was torn down to create parking. Churches played prominent roles in our history, with our proximity to St George's, Buncombe St. Methodist and First Presbyterian, which are all in walking distance of the Heritage Neighborhood. Rev. Alexander R. Mitchell served as the Bishop at Christ Episcopal Church during the first half of the 20th century. His family is still represented on Atwood St. Today Maranatha Baptist Church is still located on West Park Street. The heritage neighborhood served as home to many prominent Greenvillians. Captain John Barrett Marshall was a resident of the neighborhood and the namesake of two of our streets. Captain Marshall attended Furman University, and practiced law in Greenville. He served as mayor from 1909 until 1911 and 1913 until 1915. He worked diligently and traveled worldwide promoting Greenville. Much of the downtown paving and the Main Street Bridge over the Reedy River are monuments to his vision and energy. Captain Marshall attended Christ Episcopal Church and is buried in the adjacent cemetery. Among others, the Peace, Pearce, Gilfillin, Hughey and Mayo families were all residents of the neighborhood who have made lasting contributions to Greenville. One very interesting resident of Atwood Street was "Scoop" Latimer who for several decades was an editor at the Greenville News and was associated with Furman University sports. During the war years, almost every family in the neighborhood had sons who fought courageously for our country. Some lost their lives. Stephen Mitchell who still resides in his home of 81 years at 104 Atwood St. fought in WW II and lost a brother in Europe. Today the structure of the neighborhood remains largely intact. Mature hardwood trees abound as well as other native plants, traditional landscaping and sidewalks with granite curbs. Many residents live in family homes they have maintained for decades. There are a number of meticulously restored homes, several well-maintained in-fill homes, and several homes that are rentals. The neighborhood continues to maintain a diverse culture and a tradition of strong families. It is home to African Americans, Anglo-Saxon and Greek residents, all friends, who work together to ensure a high quality of life in the neighborhood.